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PIEZO2 / FAM38B
piezo-type mechanosensitive ion channel component 2
PIEZO2 / FAM38B contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
| Gene Name: | piezo-type mechanosensitive ion channel component 2 |
| Synonyms: | PIEZO2, C18orf58, FAM38B2, HsT748, HsT771, C18orf30, FAM38B, Protein PIEZO2 |
| Target Sequences: | NM_022068 |
Publications (1)
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