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Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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PI3 / Elafin
peptidase inhibitor 3, skin-derived
PI3 / Elafin is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
| Gene Name: | peptidase inhibitor 3, skin-derived |
| Synonyms: | PI3, Cementoin, Elafin, Elastase-specific inhibitor, ESI, PI-3, Protease inhibitor WAP3, Trappin-2, Peptidase inhibitor 3, Protease inhibitor 3, SKALP, WAP3, WFDC14, Pre-elafin |
| Target Sequences: | NM_002638 NP_002629.1 P19957 |
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