PHKB

phosphorylase kinase, beta

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

PHKB (6)

Publications

No (6)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

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PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123282

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

124.7 kDa

Price:

100 µg/$710

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Human PHKB Protein (Recombinant GST, N-terminus) (aa984-1093) - LS-G59591

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120749

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.6 kDa

Price:

100 µg/$494

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Human PHKB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66584

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.6 kDa

Price:

20 µg/$1,107

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Human PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78043

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

124.7 kDa

Price:

20 µg/$215

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Human PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78044

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.6 kDa

Price:

20 µg/$150

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