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Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes By similarity. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
Gene Name: | PHD finger protein 20 |
Synonyms: | PHF20, C20orf104, DJ1121G12.1, GLEA2, Novel zinc finger protein, PHD finger protein 20, Transcription factor TZP, NZF, TZP, Glioma-expressed antigen 2, HCA58 |
Target Sequences: | NM_016436 NP_057520.2 Q9BVI0 |
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