PHF10

PHD finger protein 10

Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

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Products

Antibodies (10)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (10)

Recombinant (3)

Target

PHF10 (15)

Reactivity

Human (10)

Mouse (1)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Monkey (3)

Rabbit (3)

Application

IHC (4)

IHC-P (1)

WB (10)

ELISA (5)

Host

rabbit (10)

Isotype

IgG (9)

Clonality

polyclonal pc (10)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (4)

Epitope

aa290-339 (4)

aa153-401 (1)

Publications

No (15)

Tag

GST (2)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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PHF10 Antibody LS-C376308

Antibody:

PHF10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PHF10 Antibody (HRP) LS-C376309

Antibody:

PHF10 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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PHF10 Antibody (Biotin) LS-C376314

Antibody:

PHF10 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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PHF10 Antibody (FITC) LS-C376315

Antibody:

PHF10 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PHF10 Antibody (aa153-401) LS-C178637

Antibody:

PHF10 Rabbit anti-Human Polyclonal (aa153-401) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$332

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PHF10 Antibody (aa290-339) LS-C81304

Antibody:

PHF10 Rabbit anti-Human Polyclonal (aa290-339) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PHF10 Antibody (aa290-339, HRP) LS-C451653

Antibody:

PHF10 Rabbit anti-Human Polyclonal (aa290-339) (HRP) Antibody

Reactivity:

Rabbit, Guinea pig, Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PHF10 Antibody (aa290-339, Biotin) LS-C451651

Antibody:

PHF10 Rabbit anti-Human Polyclonal (aa290-339) (Biotin) Antibody

Reactivity:

Rabbit, Guinea pig, Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PHF10 Antibody (aa290-339, FITC) LS-C451652

Antibody:

PHF10 Rabbit anti-Human Polyclonal (aa290-339) (FITC) Antibody

Reactivity:

Rabbit, Guinea pig, Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PHF10 Antibody LS-C750437

Antibody:

PHF10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

PHF10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111813

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.5 kDa

Price:

100 µg/$494

Select

Human PHF10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90904

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.5 kDa

Price:

20 µg/$150

Select

Human PHF10 Protein (Recombinant His, N-Terminal) - LS-G144476

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

46.5 kDa

Price:

50 µg/$419

Select

Human PHF10 Protein (Recombinant GST) (Full Length) - LS-G34262

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human PHF10 Protein (Recombinant GST) (Full Length) - LS-G34260

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.62 kDa

Price:

10 µg/$479; 25 µg/$670

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