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Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Gene Name: | peptidoglycan recognition protein 4 |
Synonyms: | PGLYRP4, PGLYRPIbeta, PGRP-I-beta, PGRPIB, SBBI67, PGRP-Ibeta |
Target Sequences: | NM_020393 NP_065126.2 Q96LB8 |
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