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PGK2

phosphoglycerate kinase 2

PGK2 is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.

Gene Name: phosphoglycerate kinase 2
Family/Subfamily: Non-protein Kinase , PGK
Synonyms: PGK2, DJ417L20.2, PGKPS, PGK-2, Phosphoglycerate kinase 2, PGKB
Target Sequences: X05246 CAA28872.1 P07205

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).