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PGK2 is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.
Gene Name: | phosphoglycerate kinase 2 |
Family/Subfamily: | Non-protein Kinase , PGK |
Synonyms: | PGK2, DJ417L20.2, PGKPS, PGK-2, Phosphoglycerate kinase 2, PGKB |
Target Sequences: | X05246 CAA28872.1 P07205 |
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