PGIS / PTGIS

prostaglandin I2 (prostacyclin) synthase

PGIS / PTGIS is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PGIS / PTGIS (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human PGIS / PTGIS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66671

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.9 kDa

Price:

20 µg/$1,107

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PGIS / PTGIS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99232

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.9 kDa

Price:

100 µg/$494

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Human PGIS / PTGIS Protein (Recombinant His-T7) (aa1-500) - LS-G24105

Source:

E. coli

Tag:

His-T7

Molecular Weight:

60.8 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human PGIS / PTGIS Protein (Recombinant GST, N-terminus) (aa391-500) - LS-G59807

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PGIS / PTGIS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78256

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.9 kDa

Price:

20 µg/$150

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Human PGIS / PTGIS Protein (Recombinant GST) (Full Length) - LS-G30022

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.5 kDa

Price:

2 µg/$439

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