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PGAM1

phosphoglycerate mutase 1 (brain)

Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.

Gene Name: phosphoglycerate mutase 1 (brain)
Synonyms: PGAM1, BPG-dependent PGAM 1, PGAMA, PGAM-B, Phosphoglycerate mutase 1
Target Sequences: NM_002629 NP_002620.1 P18669

Publications (1)

1
Dysregulation of the NUDT7-PGAM1 axis is responsible for chondrocyte death during osteoarthritis pathogenesis. Song J, Baek IJ, Chun CH, Jin EJ. Nature communications. 2018 August;9:3427. [Full Text Article] [PubMed:30143643] [PMC:PMC6109082] Related Antibodies: LS-C143463.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).