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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PFKM / PFK-1

phosphofructokinase, muscle

Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Gene Name: phosphofructokinase, muscle
Synonyms: PFKM, 6-phosphofructo-1-kinase, GSD7, PFK1, PFKA, PFKX, Phosphofructokinase-M, Phosphofructokinase 1, PFK-1, PFK-A, Phosphofructokinase, muscle, Phosphohexokinase
Target Sequences: NM_000289 NP_000280.1 P08237

Filtered by: None
Target
PFKM / PFK-1 (57)
Reactivity
Human (37)
Mouse (12)
Rat (18)
Bat (4)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (1)
Hamster (4)
Horse (1)
Orangutan (3)
Rabbit (10)
Zebrafish (4)
Application
IHC (36)
IHC-P (5)
WB (54)
ELISA (33)
ICC (2)
IF (12)
IP (4)
Peptide-ELISA (1)
Host
rabbit (44)
mouse (3)
goat (7)
sheep (3)
Isotype
IgG (27)
IgG2a,k (3)
Clonality
monoclonal mc (3)
polyclonal pc (54)
Clone
1D1 (1)
AT2F11 (1)
PAT2F11A (1)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (9)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (7)
PE Conjugated (3)
Unconjugated (25)
Epitope
aa2-390 (10)
aa122-151 (8)
aa746-776 (8)
C-Terminus (4)
Internal (2)
aa1-253 (1)
aa1-50 (1)
aa320-369 (1)
aa730-780 (1)
Publications
No (57)
Showing 1-25 of 57 results

PFKM / PFK-1 Antibody (aa320-369) IHC-plus™ LS-B12566
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
100µl 1mg/ml  $505.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of lysate from Hela cells, using PFK-1 antibody.

PFKM / PFK-1 Antibody (aa746-776) LS-C101265
Rabbit Polyclonal to Human PFKM / PFK-1
Human
IF IHC IHC-P WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PFKM Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKM antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

PFKM / PFK-1 Antibody LS-C499541
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Mouse, Human
ELISA IF IHC WB
Unconjugated
50µg  $285.00; 100µg 5mg/ml  $385.00
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA017823LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA017823LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

PFKM / PFK-1 Antibody (aa1-253) IHC-plus™ LS-B10796
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Mouse, Human
IHC IHC-P WB
Unconjugated
50µl 0.92mg/ml  $425.00
Anti-PFKM / PFK-1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. PFKM antibody diluted at 1:2000.

PFKM / PFK-1 Antibody (clone 1D1) LS-C139191
Mouse Monoclonal [clone 1D1] (IgG2a,k) to Human PFKM / PFK-1
Human
ELISA WB
Unconjugated
100µg 0.5mg/ml  $355.00
PFKM monoclonal antibody (M04), clone 1D1. Western blot of PFKM expression in K-562.
Detection limit for recombinant GST tagged PFKM is 0.3 ng/ml as a capture antibody.

PFKM / PFK-1 Antibody LS-C667606
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $335.00

PFKM / PFK-1 Antibody LS-C147414
Sheep Polyclonal to Rabbit PFKM / PFK-1
Rabbit
ELISA IF IHC WB
Unconjugated
10mg  $285.00

PFKM / PFK-1 Antibody LS-C147416
Sheep Polyclonal to Rabbit PFKM / PFK-1
Rabbit
ELISA IF IHC WB
Unconjugated
1mg  $475.00

PFKM / PFK-1 Antibody LS-C334085
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Mouse, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human esophageal cancer tissue.
Immunohistochemistry of paraffin-embedded human gastric cancer tissue.

PFKM / PFK-1 Antibody (Biotin) LS-C147415
Sheep Polyclonal to Rabbit PFKM / PFK-1
Rabbit
ELISA IF IHC WB
Biotin Conjugated
1ml  $385.00

PFKM / PFK-1 Antibody LS-C497934
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
IF IHC WB
Unconjugated
100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of HeLa cells.

PFKM / PFK-1 Antibody (aa122-151) LS-C327407
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
Unconjugated
200µl  $590.00

PFKM / PFK-1 Antibody (aa122-151, FITC) LS-C225511
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
FITC Conjugated
200µl  $740.00

PFKM / PFK-1 Antibody (aa122-151, APC) LS-C225508
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
APC Conjugated
200µl  $740.00

PFKM / PFK-1 Antibody (aa122-151, Azide-free, HRP) LS-C225512
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $740.00

PFKM / PFK-1 Antibody (aa122-151, PE) LS-C225514
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
PE Conjugated
200µl  $740.00

PFKM / PFK-1 Antibody (aa122-151, AP) LS-C225509
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
AP Conjugated
200µl  $740.00

PFKM / PFK-1 Antibody (aa746-776) LS-C327410
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
Unconjugated
200µl  $590.00

PFKM / PFK-1 Antibody (aa746-776, Biotin) LS-C225516
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
Biotin Conjugated
200µl  $740.00

PFKM / PFK-1 Antibody (aa746-776, AP) LS-C225513
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Human
ELISA IHC WB
AP Conjugated
200µl  $740.00

PFKM / PFK-1 Antibody (Internal) LS-C385467
Rabbit Polyclonal (IgG) to Human PFKM / PFK-1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of PFKM antibody

PFKM / PFK-1 Antibody (aa2-390) LS-C373155
Rabbit Polyclonal to Rat PFKM / PFK-1
Rat
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,280.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

PFKM / PFK-1 Antibody LS-C209185
Goat Polyclonal to Rabbit PFKM / PFK-1
Rabbit
ELISA IF WB
Unconjugated
100µg 1mg/ml  $425.00

PFKM / PFK-1 Antibody (Internal) LS-C358834
Rabbit Polyclonal to Human PFKM / PFK-1
Human
IHC IHC-P WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Immunohistochemical analysis of PFKM staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of PFKM expression in SHSY5Y (A); A549 (B); Ramos (C) whole cell lysates.

PFKM / PFK-1 Antibody (aa122-151) LS-C101264
Rabbit Polyclonal to Human PFKM / PFK-1
Human
IHC IHC-P WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot of lysate from human skeletal muscle tissue lysate, using PFKM Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Showing 1-25 of 57 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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