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PEMT

phosphatidylethanolamine N-methyltransferase

Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Name: phosphatidylethanolamine N-methyltransferase
Synonyms: PEMT, PEAMT, PEMPT, PEMT2
Target Sequences: NM_007169 NP_009100.2 Q9UBM1

Publications (1)

1
Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation. Hughey CC, James FD, Wang Z, Goelzer M, Wasserman DH. Molecular metabolism. 2019 May;23:1-13. [Full Text Article] [PubMed:30850319] [PMC:PMC6479583] Related Antibodies: LS-C163519.

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Proteins (8)
Over-Expression Lysate (6)
Recombinant (2)
PEMT (8)
No (8)
GST (1)
Myc-DDK (Flag) (7)
Human (5)
293T Cells (3)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (1)
PEMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
100 µg/$494
PEMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
100 µg/$494
PEMT Protein - 12.5% SDS-PAGE of human PEMT stained with Coomassie Blue
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Wheat Germ Extract
GST
52.3 kDa
10 µg/$479; 25 µg/$670
PEMT Protein - Purified recombinant protein PEMT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
20 µg/$1,107
PEMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
22 kDa
20 µg/$150
PEMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.7 kDa
20 µg/$150
PEMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22 kDa
20 µg/$150
PEMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).