PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

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Antibodies (28)

Proteins (7)

ELISA Kits (2)

Type

Over-Expression Lysate (4)

Primary (28)

Recombinant (3)

Sandwich (1)

Sandwich CLIA (1)

Target

PDP1 (37)

Reactivity

Human (30)

Mouse (8)

Rat (6)

Bovine (1)

Application

IHC (11)

IHC-P (2)

WB (24)

ELISA (10)

Peptide-ELISA (1)

Host

rabbit (28)

Isotype

IgG (16)

Clonality

polyclonal pc (28)

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12 x 8-Well Microstrips (1)

96-Well Strip Plate (1)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (13)

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Epitope

aa315-537 (8)

aa308-336 (7)

Internal (1)

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No (37)

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Plasma (1)

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Tissue Homogenates (1)

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His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

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PDP1 Antibody (aa308-336) LS-C163497

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PDP1 Antibody LS-C673929

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PDP1 Antibody (aa308-336) LS-C329958

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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PDP1 Antibody (aa308-336, Biotin) LS-C238893

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PDP1 Antibody (aa308-336, FITC) LS-C238894

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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PDP1 Antibody (aa308-336, Azide-free, HRP) LS-C248443

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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PDP1 Antibody (aa308-336, APC) LS-C238892

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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PDP1 Antibody (aa308-336, PE) LS-C238896

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa308-336) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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PDP1 Antibody LS-C334646

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PDP1 Antibody LS-C768956

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PDP1 Antibody LS-C401943

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PDP1 Antibody LS-C754194

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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PDP1 Antibody LS-C779964

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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PDP1 Antibody LS-C808217

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PDP1 Antibody LS-C749549

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PDP1 Antibody LS-C411840

Antibody:

PDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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PDP1 Antibody (Internal) LS-C354451

Antibody:

PDP1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Bovine, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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PDP1 Antibody (aa315-537) LS-C296167

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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PDP1 Antibody (aa315-537, HRP) LS-C708605

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439

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PDP1 Antibody (aa315-537, Biotin) LS-C685198

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

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PDP1 Antibody (aa315-537, FITC) LS-C691611

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$334; 200 µl/$387; 500 µl/$565; 1 ml/$682; 2 ml/$919; 5 ml/$1,549

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PDP1 Antibody (aa315-537, PE) LS-C722664

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213

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PDP1 Antibody (aa315-537, APC) LS-C716276

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213

Select

PDP1 Antibody (aa315-537, APC, Cy7) LS-C731667

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$476; 200 µl/$590; 500 µl/$1,069; 1 ml/$1,265; 2 ml/$1,771; 5 ml/$3,319

Select

PDP1 Antibody (aa315-537, Cy3) LS-C699584

Antibody:

PDP1 Rabbit anti-Human Polyclonal (aa315-537) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC
• APC, Cy7
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC
  • APC, Cy7
  • Cy3

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