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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PDE6D / PDE6 Delta

phosphodiesterase 6D, cGMP-specific, rod, delta

Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.

Gene Name: phosphodiesterase 6D, cGMP-specific, rod, delta
Family/Subfamily: Phosphodiesterase , PDE - photoreceptor
Synonyms: PDE6D, GMP-PDE delta, PDED, Phosphodiesterase 6d, Phosphodiesterase delta, Protein p17, Pde delta
Target Sequences: NM_002601 NP_002592.1 O43924

Filtered By: None
Target
PDE6D / PDE6 Delta (20)
Reactivity
Human (19)
Mouse (14)
Chimpanzee (3)
Monkey (4)
Sheep (1)
Application
IHC (6)
IHC-Fr (1)
IHC-P (2)
WB (20)
ELISA (12)
ICC (2)
IF (2)
Host
rabbit (19)
mouse (1)
Isotype
IgG (13)
IgG2b,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (19)
Clone
4H6 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
Epitope
aa26-55 (8)
aa21-70 (4)
aa1-150 (1)
Publications
No (20)
Showing 1-20 of 20 results

PDE6D / PDE6 Delta Antibody LS-C355607
Rabbit Polyclonal (IgG) to Mouse PDE6D / PDE6 Delta
Mouse, Sheep
ICC IF IHC IHC-Fr WB
Unconjugated
100µg 1mg/ml  $425.00
IF using PDE6 delta Antibody
IF using PDE6 delta Antibody
IF using PDE6 delta Antibody
IF using PDE6 delta Antibody

PDE6D / PDE6 Delta Antibody (aa21-70) LS-C206193
Rabbit Polyclonal to Human PDE6D / PDE6 Delta
Human, Monkey
WB
Unconjugated
50µg  $365.00
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE6D / PDE6 Delta Antibody (aa21-70, HRP) LS-C479738
Rabbit Polyclonal to Human PDE6D / PDE6 Delta
Human, Monkey, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE6D / PDE6 Delta Antibody (aa21-70, Biotin) LS-C479736
Rabbit Polyclonal to Human PDE6D / PDE6 Delta
Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE6D / PDE6 Delta Antibody (aa21-70, FITC) LS-C479737
Rabbit Polyclonal to Human PDE6D / PDE6 Delta
Human, Monkey, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE6D / PDE6 Delta Antibody (aa26-55) LS-C158561
Rabbit Polyclonal to Human PDE6D / PDE6 Delta
Mouse, Human
WB
Unconjugated
400µl  $305.00
PDE6D Antibody western blot of A2058 cell line lysates (35 ug/lane). The PDE6D antibody detected the PDE6D protein (arrow).
PDE6D Antibody western blot of mouse heart tissue lysates (35 ug/lane). The PDE6D antibody detected the PDE6D protein (arrow).
PDE6D Antibody western blot of A2058 cell line lysates (35 ug/lane). The PDE6D antibody detected the PDE6D protein (arrow).
PDE6D Antibody western blot of mouse heart tissue lysates (35 ug/lane). The PDE6D antibody detected the PDE6D protein (arrow).

PDE6D / PDE6 Delta Antibody (aa1-150) LS-C186054
Rabbit Polyclonal to Human PDE6D / PDE6 Delta
Human
ICC IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded SAS xenograft using PDE6D antibody at 1:500 dilution.
Immunofluorescence of methanol-fixed HeLa using PDE6D antibody at 1:500 dilution.
IHC of paraffin-embedded SAS xenograft using PDE6D antibody at 1:500 dilution.
Immunofluorescence of methanol-fixed HeLa using PDE6D antibody at 1:500 dilution.

PDE6D / PDE6 Delta Antibody LS-C377270
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human small intestine tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human small intestine tissue using antibody at dilution of 1:100.

PDE6D / PDE6 Delta Antibody (HRP) LS-C377269
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA IHC WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00

PDE6D / PDE6 Delta Antibody (Biotin) LS-C377271
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA IHC WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

PDE6D / PDE6 Delta Antibody (FITC) LS-C377268
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA IHC WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00

PDE6D / PDE6 Delta Antibody (clone 4H6) LS-C197861
Mouse Monoclonal [clone 4H6] (IgG2b,k) to Human PDE6D / PDE6 Delta
Human
ELISA IF WB
Unconjugated
100µg 1mg/ml  $355.00
Immunofluorescence of monoclonal antibody to PDE6D on HeLa cell . [antibody concentration 10 ug/ml]
Immunofluorescence of monoclonal antibody to PDE6D on HeLa cell . [antibody concentration 10 ug/ml]

PDE6D / PDE6 Delta Antibody (aa26-55) LS-C329957
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
Unconjugated
200µl  $530.00

PDE6D / PDE6 Delta Antibody (aa26-55, Biotin) LS-C265901
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
Biotin Conjugated
200µl  $680.00

PDE6D / PDE6 Delta Antibody (aa26-55, FITC) LS-C265902
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
FITC Conjugated
200µl  $680.00

PDE6D / PDE6 Delta Antibody (aa26-55, AP) LS-C265898
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
AP Conjugated
200µl  $680.00

PDE6D / PDE6 Delta Antibody (aa26-55, APC) LS-C265900
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
APC Conjugated
200µl  $680.00

PDE6D / PDE6 Delta Antibody (aa26-55, Azide-free, HRP) LS-C265903
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

PDE6D / PDE6 Delta Antibody (aa26-55, PE) LS-C265904
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
ELISA WB
PE Conjugated
200µl  $680.00

PDE6D / PDE6 Delta Antibody LS-C749746
Rabbit Polyclonal (IgG) to Human PDE6D / PDE6 Delta
Mouse, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of various cell lines, using PDE6D antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Western blot analysis of extracts of various cell lines, using PDE6D antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Showing 1-20 of 20 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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