LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

PDE12

phosphodiesterase 12

Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

Gene Name: phosphodiesterase 12
Synonyms: PDE12, 2'-PDE, 2,5-phosphodiesterase 12, 2-PDE, 2-phosphodiesterase, Phosphodiesterase 12
Target Sequences: AK001526 NP_808881.3 Q6L8Q7

Filtered By: None
Target
PDE12 (27)
Reactivity
Human (17)
Mouse (18)
Rat (8)
Bat (4)
Bovine (8)
Chicken (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (8)
Hamster (4)
Horse (8)
Monkey (4)
Pig (8)
Rabbit (4)
Zebrafish (4)
Application
IHC (8)
WB (27)
Flo (8)
ELISA (8)
ICC (2)
IF (1)
Host
rabbit (27)
Isotype
IgG (18)
Clonality
polyclonal pc (27)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (6)
Epitope
aa290-602 (10)
aa362-390 (8)
C-Terminus (4)
aa368-417 (4)
Publications
No (27)
Showing 1-25 of 27 results

PDE12 Antibody (aa362-390) LS-C163466
Rabbit Polyclonal to Human PDE12
Human
Flo WB
Unconjugated
400µl  $305.00
PDE12 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PDE12 antibody detected the PDE12 protein (arrow).
PDE12 Antibody flow cytometry of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
PDE12 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PDE12 antibody detected the PDE12 protein (arrow).
PDE12 Antibody flow cytometry of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

PDE12 Antibody (aa368-417) LS-C186696
Rabbit Polyclonal to Human PDE12
Zebrafish, Pig, Horse, Rat, Mouse, Guinea pig, Bovine, Human
WB
Unconjugated
50µg  $365.00
Western blot of Human Ovary Tumor. PDE12 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Ovary Tumor. PDE12 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE12 Antibody (aa368-417, HRP) LS-C457433
Rabbit Polyclonal to Human PDE12
Zebrafish, Pig, Horse, Mouse, Guinea pig, Bovine, Rat, Human, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Western blot of Human Ovary Tumor. PDE12 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Ovary Tumor. PDE12 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE12 Antibody (aa368-417, FITC) LS-C457432
Rabbit Polyclonal to Human PDE12
Zebrafish, Pig, Horse, Mouse, Guinea pig, Bovine, Rat, Human, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
Western blot of Human Ovary Tumor. PDE12 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Ovary Tumor. PDE12 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE12 Antibody LS-C667544
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA IF WB
Unconjugated
100µg  $355.00

PDE12 Antibody (aa362-390) LS-C323884
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
Unconjugated
200µl  $530.00

PDE12 Antibody (aa362-390, Biotin) LS-C207421
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
Biotin Conjugated
200µl  $680.00

PDE12 Antibody (aa362-390, FITC) LS-C207422
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
FITC Conjugated
200µl  $680.00

PDE12 Antibody (aa362-390, AP) LS-C207418
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
AP Conjugated
200µl  $680.00

PDE12 Antibody (aa362-390, APC) LS-C207419
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
APC Conjugated
200µl  $680.00

PDE12 Antibody (aa362-390, PE) LS-C207425
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
PE Conjugated
200µl  $680.00

PDE12 Antibody (aa362-390, Azide-free, HRP) LS-C207424
Rabbit Polyclonal (IgG) to Human PDE12
Human
ELISA Flo WB
HRP Conjugated, Azide-free
200µl  $680.00

PDE12 Antibody (aa290-602) LS-C373386
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, HRP) LS-C713441
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,805.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, Biotin) LS-C423941
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

PDE12 Antibody (aa290-602, Biotin) LS-C688596
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $315.00; 1ml  $590.00; 10ml  $2,370.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, FITC) LS-C423940
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

PDE12 Antibody (aa290-602, FITC) LS-C695595
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, APC, Cy7) LS-C736423
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $465.00; 200µl  $650.00; 1ml  $1,620.00; 10ml  $6,480.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, PE) LS-C727509
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, Cy3) LS-C704424
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $365.00; 200µl  $445.00; 1ml  $1,080.00; 10ml  $4,320.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (aa290-602, APC) LS-C741534
Rabbit Polyclonal (IgG) to Mouse PDE12
Mouse
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $315.00; 200µl  $375.00; 1ml  $815.00
Western blot of PDE12 antibody.
Western blot of PDE12 antibody.

PDE12 Antibody (C-Terminus) LS-C111507
Rabbit Polyclonal to Human PDE12
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
PDE12 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE12 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE12 Antibody (C-Terminus, Biotin) LS-C457434
Rabbit Polyclonal to Human PDE12
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
PDE12 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE12 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PDE12 Antibody (C-Terminus, FITC) LS-C457435
Rabbit Polyclonal to Human PDE12
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
PDE12 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PDE12 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 27 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy