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Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination.
Gene Name: | Phosducin-like 3 |
Synonyms: | PDCL3, HTPHLP, PHLP2A, VIAF1, Viral IAP-associated factor 1, PHLP3, Phosducin-like protein 3, PhPL3, VIAF, IAP-associated factor VIAF1, Phosducin-like 3, VIAF-1 |
Target Sequences: | NM_024065 NP_076970.1 Q9H2J4 |
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