PDCD6 / ALG-2

programmed cell death 6

Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca2+-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca2+ affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

PDCD6 / ALG-2 (8)

Publications

No (8)

Tag

GST (2)

GST, N-terminus (1)

His (1)

His-S (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human PDCD6 / ALG-2 Protein (Recombinant GST, N-terminus) (aa92-191) - LS-G61324

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PDCD6 / ALG-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89774

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

20 µg/$150

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PDCD6 / ALG-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114391

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

100 µg/$494

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Human PDCD6 / ALG-2 Protein (Recombinant GST) (Full Length) - LS-G22253

Source:

E. coli

Tag:

GST

Molecular Weight:

49.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PDCD6 / ALG-2 Protein (Recombinant His-S) (aa32-191) - LS-G26089

Source:

E. coli

Tag:

His-S

Molecular Weight:

22.5 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human PDCD6 / ALG-2 Protein (Recombinant GST) (Full Length) - LS-G31901

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

46.75 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PDCD6 / ALG-2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71438

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

20 µg/$1,107

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Human PDCD6 / ALG-2 Protein (Recombinant His) - LS-G1199

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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