PCSK4

proprotein convertase subtilisin/kexin type 4

PCSK4 / PC4 is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PCSK4 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PCSK4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92773

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.6 kDa

Price:

20 µg/$215

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PCSK4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112386

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.6 kDa

Price:

100 µg/$710

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Human PCSK4 Protein (Recombinant GST) (Full Length) - LS-G34044

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.36 kDa

Price:

10 µg/$479; 25 µg/$670

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