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Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis.
Gene Name: | protocadherin 8 |
Family/Subfamily: | Cadherin , not assigned-Cadherin |
Synonyms: | PCDH8, ARCADLIN, Protocadherin 8, Protocadherin-8, PAPC |
Target Sequences: | NM_002590 NP_002581.2 O95206 |
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