Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
PCDH12 / VE-Cadherin-2 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
Gene Name: | protocadherin 12 |
Family/Subfamily: | Cadherin , not assigned-Cadherin |
Synonyms: | PCDH12, Pcdh14, Protocadherin 12, Protocadherin 14, Vascular cadherin-2, VE-cad-2, VE-cadherin 2, VECAD2, Protocadherin-12, VE-cadherin-2 |
Target Sequences: | NM_016580 NP_057664.1 Q9NPG4 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.