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PCDH1 / PCD1 belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Gene Name: | protocadherin 1 |
Family/Subfamily: | Cadherin , not assigned-Cadherin |
Synonyms: | PCDH1, Cadherin-like protein 1, PC42, Protocadherin-42, Protocadherin 1, Protocadherin-1, PCDH42, Protocadherin 42, Cadherin-like 1, PCD1 |
Target Sequences: | NM_002587 NP_002578.2 Q08174 |
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