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PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
Gene Name: | pre-B-cell leukemia homeobox 2 |
Synonyms: | PBX2, HOX12, Homeobox protein PBX2, Protein G17, G17, Homeobox 12, PBX2MHC, Pre-B-cell leukemia homeobox 2 |
Target Sequences: | NM_002586 NP_002577.2 P40425 |
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