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RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
Gene Name: | protein associated with topoisomerase II homolog 1 (yeast) |
Synonyms: | PATL1, HPat1b, PAT1-like protein 1, Protein PAT1 homolog b, Protein PAT1 homolog 1, Pat1b |
Target Sequences: | NM_152716 NP_689929.2 Q86TB9 |
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