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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PARP3

poly (ADP-ribose) polymerase family, member 3

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Gene Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: PARP3, ADPRT-3, ADPRTL2, ADPRTL3, ARTD3, ADPRT3, HPARP-3, PADPRT-3, Poly[ADP-ribose] synthase 3, Poly[ADP-ribose] synthetase 3, PARP-3, Poly [ADP-ribose] polymerase 3, IRT1, NAD+ ADP-ribosyltransferase 3, Poly(ADP-ribose) synthetase-3
Target Sequences: NM_005485 NP_005476.4 Q9Y6F1

Filtered By: None
Target
PARP3 (26)
Reactivity
Human (26)
Mouse (8)
Rat (6)
Bat (4)
Chimpanzee (3)
Horse (4)
Monkey (4)
Rabbit (4)
Application
IHC (19)
IHC-P (11)
WB (16)
ELISA (13)
ICC (1)
IF (3)
Peptide-ELISA (2)
Host
rabbit (25)
goat (1)
Isotype
IgG (20)
Clonality
polyclonal pc (26)
Format
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (20)
Epitope
aa446-495 (4)
aa294-533 (2)
10-90 aa, N-terminal (1)
N-Terminus (1)
aa10-59 (1)
aa451-481 (1)
aa63-370 (1)
aa90-104 (1)
aa99-126 (1)
Publications
No (26)
Showing 1-25 of 26 results

PARP3 Antibody (aa10-59) IHC-plus™ LS-B7682
Rabbit Polyclonal (IgG) to Human PARP3
Human
IHC IHC-P Peptide-ELISA
Unconjugated
50µl 1mg/ml  $425.00
Anti-PARP3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Anti-PARP3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.

PARP3 Antibody (aa451-481) LS-C100025
Rabbit Polyclonal to Mouse PARP3
Mouse, Human
WB
Unconjugated
400µl  $305.00
Western blot of anti-PARP3 antibody in mouse spleen tissue lysates (35 ug/lane). PARP3(arrow) was detected using the purified antibody.
Western blot of anti-PARP3 antibody in mouse spleen tissue lysates (35 ug/lane). PARP3(arrow) was detected using the purified antibody.

PARP3 Antibody (aa63-370) LS-C185525
Rabbit Polyclonal (IgG) to Human PARP3
Human
ICC IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded OVCA using PARP3 antibody at 1:100 dilution.
Immunofluorescence of paraformaldehyde-fixed HeLa using PARP3 antibody at 1:500 dilution.
IHC of paraffin-embedded OVCA using PARP3 antibody at 1:100 dilution.
Immunofluorescence of paraformaldehyde-fixed HeLa using PARP3 antibody at 1:500 dilution.

PARP3 Antibody LS-C667471
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

PARP3 Antibody (aa90-104) IHC-plus™ LS-B4379
Goat Polyclonal to Human PARP3
Human
IHC IHC-P Peptide-ELISA
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-PARP3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-PARP3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-PARP3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-PARP3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

PARP3 Antibody LS-C681003
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.

PARP3 Antibody (HRP) LS-C681007
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

PARP3 Antibody (Biotin) LS-C681005
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

PARP3 Antibody (aa294-533) LS-C376270
Rabbit Polyclonal (IgG) to Human PARP3
Mouse, Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Western blot. All lanes: Poly [ADP-ribose] polymerase 3 antibody at 2 ug/ml+mouse heart tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Western blot. All lanes: Poly [ADP-ribose] polymerase 3 antibody at 2 ug/ml+mouse heart tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa.

PARP3 Antibody (aa294-533) LS-C376271
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Western blot. All lanes: Poly [ADP-ribose] polymerase 3 antibody at 7 ug/ml+mouse kidney tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Western blot. All lanes: Poly [ADP-ribose] polymerase 3 antibody at 7 ug/ml+mouse kidney tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa.

PARP3 Antibody LS-C412835
Rabbit Polyclonal to Human PARP3
Human
IF IHC WB
Unconjugated
100µl  $385.00

PARP3 Antibody LS-C346339
Rabbit Polyclonal (IgG) to Human PARP3
Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of MCF7 cells.
Immunofluorescence analysis of MCF7 cells.

PARP3 Antibody (aa446-495) LS-C29728
Rabbit Polyclonal (IgG) to Human PARP3
Rabbit, Mouse, Rat, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $365.00
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PARP3 Antibody (aa446-495, HRP) LS-C430097
Rabbit Polyclonal (IgG) to Human PARP3
Rabbit, Mouse, Rat, Horse, Bat, Chimpanzee, Human, Monkey
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PARP3 Antibody (aa446-495, Biotin) LS-C430094
Rabbit Polyclonal (IgG) to Human PARP3
Rabbit, Mouse, Rat, Horse, Bat, Chimpanzee, Human, Monkey
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PARP3 Antibody (aa446-495, FITC) LS-C430096
Rabbit Polyclonal (IgG) to Human PARP3
Rabbit, Mouse, Rat, Horse, Bat, Chimpanzee, Human, Monkey
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PARP3 Antibody (N-Terminus) LS-C356240
Rabbit Polyclonal to Human PARP3
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of PARP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of PARP3 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
Immunohistochemical analysis of PARP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of PARP3 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.

PARP3 Antibody (10-90 aa, N-terminal) LS-C385364
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC
Unconjugated
100µl 1mg/ml  $265.00

PARP3 Antibody LS-C401920
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using PARP3 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human liver cancer using PARP3 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human liver cancer using PARP3 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human liver cancer using PARP3 Polyclonal Antibody at dilution of 1:40.

PARP3 Antibody LS-C405233
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using PARP3 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human thyroid cancer using PARP3 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human thyroid cancer using PARP3 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human thyroid cancer using PARP3 Polyclonal Antibody at dilution of 1:25.

PARP3 Antibody LS-C403407
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human colon cancer using PARP3 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human colon cancer using PARP3 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human colon cancer using PARP3 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human colon cancer using PARP3 Polyclonal Antibody at dilution of 1:30.

PARP3 Antibody LS-C406649
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human cervical cancer using PARP3 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human cervical cancer using PARP3 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human cervical cancer using PARP3 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human cervical cancer using PARP3 Polyclonal Antibody at dilution of 1:20.

PARP3 Antibody LS-C136864
Rabbit Polyclonal (IgG) to Human PARP3
Human
ELISA WB
Unconjugated
100µl  $255.00
Western blot Image
Western blot Image

PARP3 Antibody (aa99-126) LS-C203978
Rabbit Polyclonal to Human PARP3
Human
WB
Unconjugated
400µl  $305.00
PARP3 Antibody western blot of K562,MDA-MB453,NCI-H292,A549,293,HeLa,CEM,NCI-H460 cell line and human normal uterus tissue lysates (35 ug/lane). The PARP3 antibody detected the PARP3 protein (arrow).
PARP3 Antibody western blot of K562,MDA-MB453,NCI-H292,A549,293,HeLa,CEM,NCI-H460 cell line and human normal uterus tissue lysates (35 ug/lane). The PARP3 antibody detected the PARP3 protein (arrow).

PARP3 Antibody LS-C412078
Rabbit Polyclonal to Human PARP3
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot of PARP3 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: RAW264.7 whole cell lysate.
Western blot of PARP3 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: RAW264.7 whole cell lysate.
Showing 1-25 of 26 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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