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PAPPA / PAPP-A
pregnancy-associated plasma protein A, pappalysin 1
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
| Gene Name: | pregnancy-associated plasma protein A, pappalysin 1 |
| Family/Subfamily: | Protease , Metallopeptidase M43 |
| Synonyms: | PAPPA, DIPLA1, IGF-dependent IGFBP-4 protease, PAPPA1, PAPA, PAPP-A, Pappalysin-1, ASBABP2, IGFBP-4ase |
| Target Sequences: | NM_002581 NP_002572.2 Q13219 |
Publications (1)
1
Persistent DNA Damage and Senescence in the Placenta Impacts Developmental Outcomes of Embryos. Vijay Pratap Singh, Sean McKinney, Jennifer L Gerton. The Breast : official journal of the European Society of Mastology. 2020 Aug;54:333-347.e7. [Full Text Article]
[PubMed:32800293]
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(95)
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PAPPA / PAPP-A
(95)
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(87)
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(11)
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(8)
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(60)
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(51)
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(2)
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(34)
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(42)
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(53)
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(2)
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(12)
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(2)
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(24)
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(18)
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(53)
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(42)
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(2)
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(11)
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(4)
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(4)
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(12)
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(11)
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(10)
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(33)
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aa244-501
(10)
aa1270-1558
(8)
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aa999-1272
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aa95-388
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Publications
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(95)
PAPPA / PAPP-A Mouse anti-Human Monoclonal (1G3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
PAPPA / PAPP-A Rabbit anti-Mouse Polyclonal (aa999-1272) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PAPPA / PAPP-A Mouse anti-Human Monoclonal (7A6) Antibody
Human
IP
Unconjugated
0.2 mg/$407; 0.5 mg/$487
PAPPA / PAPP-A Mouse anti-Human Monoclonal (5H9) Antibody
Human
IP
Unconjugated
0.2 mg/$407; 0.5 mg/$487
PAPPA / PAPP-A Mouse anti-Human Monoclonal (10E1) Antibody
Human
ELISA, IP, WB
Unconjugated
0.2 mg/$486
PAPPA / PAPP-A Rabbit anti-Human Polyclonal (aa95-388) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PAPPA / PAPP-A Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IP, WB
HRP Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IP, WB
Biotin Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IP, WB
FITC Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IP, WB
APC Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IP, WB
PE Conjugated
100 µl/$1,085
PAPPA / PAPP-A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
PAPPA / PAPP-A Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
200 µg/$757
PAPPA / PAPP-A Mouse anti-Human Monoclonal (4G11) Antibody
Human
IP
Unconjugated
0.2 mg/$407; 0.5 mg/$487
PAPPA / PAPP-A Mouse anti-Human Monoclonal (1_1) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$1,090
PAPPA / PAPP-A Mouse anti-Human Monoclonal (1_24) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$1,043
PAPPA / PAPP-A Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$1,090
PAPPA / PAPP-A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PAPPA / PAPP-A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P
Unconjugated
60 µl/$460
PAPPA / PAPP-A Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IP, WB
HRP Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IP, WB
Biotin Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IP, WB
FITC Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IP, WB
APC Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IP, WB
PE Conjugated
100 µl/$1,085
PAPPA / PAPP-A Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP
Unconjugated
1 mg/$925
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of 95
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