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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PAN2 / USP52

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.

Gene Name: PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
Synonyms: PAN2, PYPAF4, Ubiquitin specific protease 52, USP52
Target Sequences: NM_001127460 NP_001120932.1 Q504Q3

Filtered by: None
Target
PAN2 / USP52 (15)
Reactivity
Human (15)
Mouse (2)
Application
IHC (2)
IHC-P (1)
WB (11)
ELISA (12)
IF (1)
IP (1)
Host
rabbit (15)
Isotype
IgG (14)
Clonality
polyclonal pc (15)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (6)
Epitope
aa860-888 (8)
aa1-50 (1)
Publications
No (15)
Showing 1-15 of 15 results

PAN2 / USP52 Antibody LS-C678934
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human liver tissue at dilution of 1:100
Immunofluorescent analysis of HepG-2 cells diluted at 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

PAN2 / USP52 Antibody (HRP) LS-C678937
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

PAN2 / USP52 Antibody (Biotin) LS-C678935
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

PAN2 / USP52 Antibody (FITC) LS-C678936
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

PAN2 / USP52 Antibody LS-C667450
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, IHC, WB
Unconjugated
100µg  $355.00

PAN2 / USP52 Antibody (aa860-888) LS-C329946
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
Unconjugated
200µl  $590.00

PAN2 / USP52 Antibody (aa860-888, Biotin) LS-C216601
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

PAN2 / USP52 Antibody (aa860-888, FITC) LS-C216602
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

PAN2 / USP52 Antibody (aa860-888, AP) LS-C216598
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
AP Conjugated
200µl  $740.00

PAN2 / USP52 Antibody (aa860-888, APC) LS-C216599
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
APC Conjugated
200µl  $740.00

PAN2 / USP52 Antibody (aa860-888, PE) LS-C216604
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
PE Conjugated
200µl  $740.00

PAN2 / USP52 Antibody (aa860-888, Azide-free, HRP) LS-C216603
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

PAN2 / USP52 Antibody (aa1-50) LS-C762401
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Mouse, Human
IP, WB
Unconjugated
100µg 100µl 1mg/ml  $395.00
Detection of human and mouse PAN2/USP52 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PAN2/USP52 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

PAN2 / USP52 Antibody (aa860-888) LS-C163352
Rabbit Polyclonal to Human PAN2 / USP52
Human
WB
Unconjugated
400µl  $325.00
PAN2 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The PAN2 antibody detected the PAN2 protein (arrow).

PAN2 / USP52 Antibody LS-C750343
Rabbit Polyclonal (IgG) to Human PAN2 / USP52
Mouse, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using PAN2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
Showing 1-15 of 15 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).