Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Gene Name: | poly(A) binding protein interacting protein 1 |
Synonyms: | PAIP1, PABC1-interacting protein 1, PABP-interacting protein 1, PAIP-1 |
Target Sequences: | NM_006451 NP_006442.2 Q9H074 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.