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PAG1

phosphoprotein associated with glycosphingolipid microdomains 1

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Gene Name: phosphoprotein associated with glycosphingolipid microdomains 1
Synonyms: PAG1, Csk-binding protein, CBP, PAG
Target Sequences: NM_018440 NP_060910.3 Q9NWQ8

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
PAG1 (5)
No (5)
His (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Bovine (1)
Human (1)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Low endotoxin level (1)
PAG1 Protein - Recombinant  Phosphoprotein Associated With Glycosphingolipid Microdomains 1 By SDS-PAGE
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E. coli
His-T7
28.6 kDa
10 µg/$271; 50 µg/$422; 100 µg/$674; 200 µg/$841; 1 mg/$1,880
PAG1 Protein - Recombinant  Phosphoprotein Associated With Glycosphingolipid Microdomains 1 By SDS-PAGE
Select
E. coli
His-T7
27.4 kDa
10 µg/$276; 50 µg/$450; 100 µg/$720; 200 µg/$898; 1 mg/$1,980
PAG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$200
PAG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
100 µg/$607
Select
E. coli
99 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
11 kDa
10 mg/$4,268; 5 mg/$3,202; 1 mg/$1,868; 0.5 mg/$1,362; 200 µg/$1,023; 100 µg/$710; 50 µg/$521
Viewing 1-5 of 5 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).