PABPC1 / PABP1

poly(A) binding protein, cytoplasmic 1

Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons; for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed.

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Products

Antibodies (16)

Type

Primary (16)

Target

PABPC1 / PABP1 (16)

Reactivity

Human (16)

Mouse (10)

Rat (9)

Bovine (3)

Chicken (5)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (5)

Sheep (3)

Xenopus (2)

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Application

IHC (4)

IHC-P (3)

WB (16)

Flo (1)

ELISA (6)

ICC (1)

IF (3)

IP (3)

Host

rabbit (14)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (11)

IgG2b (2)

Clonality

monoclonal mc (2)

polyclonal pc (14)

Clone

10E10 (2)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Preservative Free (1)

Unconjugated (13)

Epitope

aa431-480 (4)

aa394-636 (2)

aa250-279 (1)

Publications

No (16)

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PABPC1 / PABP1 Antibody LS-C753951

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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IHC-plus™ PABPC1 / PABP1 Antibody (aa394-636) LS-B8470

(4.0) Rating

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa394-636) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$485

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PABPC1 / PABP1 Antibody LS-C778021

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

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PABPC1 / PABP1 Antibody (aa431-480) LS-C101839

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PABPC1 / PABP1 Antibody (aa431-480, HRP) LS-C440279

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) (HRP) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PABPC1 / PABP1 Antibody (aa431-480, Biotin) LS-C440277

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) (Biotin) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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PABPC1 / PABP1 Antibody (aa431-480, FITC) LS-C440278

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) (FITC) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PABPC1 / PABP1 Antibody (clone 10E10) LS-C82271

Antibody:

PABPC1 / PABP1 Mouse anti-Human Monoclonal (10E10) Antibody

Reactivity:

Xenopus, Chicken, Rabbit, Human

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$429

Select

PABPC1 / PABP1 Antibody (clone 10E10) LS-C82229

Antibody:

PABPC1 / PABP1 Mouse anti-Human Monoclonal (10E10) Antibody

Reactivity:

Xenopus, Chicken, Rabbit, Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$482

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PABPC1 / PABP1 Antibody (aa250-279) LS-C163331

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa250-279) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PABPC1 / PABP1 Antibody (aa394-636) LS-C144925

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa394-636) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

Select

PABPC1 / PABP1 Antibody (Preservative Free) LS-C814969

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

PABPC1 / PABP1 Antibody LS-C405147

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

PABPC1 / PABP1 Antibody LS-C401836

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

PABPC1 / PABP1 Antibody LS-C768832

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

PABPC1 / PABP1 Antibody LS-C749853

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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