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PAAF1

Proteasomal ATPase-associated factor 1

Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.

Gene Name: Proteasomal ATPase-associated factor 1
Synonyms: PAAF1, PAAF, Protein G-16, WD repeat domain 71, Rpn14, WDR71
Target Sequences: NM_025155 NP_079431.1 Q9BRP4

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
PAAF1 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
PAAF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42 kDa
100 µg/$494
PAAF1 Protein - 12.5% SDS-PAGE of human PAAF1 stained with Coomassie Blue
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Wheat Germ Extract
GST
66.8 kDa
2 µg/$439
PAAF1 Protein - Purified recombinant protein PAAF1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42 kDa
20 µg/$1,107
PAAF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
42 kDa
20 µg/$150
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).