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Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP+. Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH.
Gene Name: | pyrroline-5-carboxylate reductase family, member 2 |
Synonyms: | PYCR2, p5CR 2, p5C reductase 2, p5CR2 |
Target Sequences: | NM_013328 NP_037460.2 Q96C36 |
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