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P2RY1 / P2Y1
purinergic receptor P2Y, G-protein coupled, 1
P2RY1 / P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
| Gene Name: | purinergic receptor P2Y, G-protein coupled, 1 |
| Family/Subfamily: | GPCR , Purinergic |
| Synonyms: | P2RY1, ATP receptor, p2Y1, p2y1r, Platelet ADP receptor, Purinoceptor p2y1, Purinergic receptor, p2 purinoceptor subtype Y1, p2RY1, p2Y purinoceptor 1, p2y-1-r, Purinoceptor p2yr1, p2y1 receptor, P2YR, Purinergic receptor P2Y, G-protein coupled, 1 |
| Target Sequences: | NM_002563 NP_002554.1 P47900 |
Publications (1)
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