Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

P2RX7 / P2X7

purinergic receptor P2X, ligand-gated ion channel, 7

P2RX7 / P2X7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Gene Name: purinergic receptor P2X, ligand-gated ion channel, 7
Family/Subfamily: Ion Channel , P2X receptor
Synonyms: P2RX7, ATP receptor, p2X purinoceptor 7, p2X receptor 7, p2X7 purinoceptor, p2Z receptor, Purinergic receptor, p2RX7, p2X7, p2X7 receptor
Target Sequences: NM_002562 NP_002553.3 Q99572

Publications (2)

1
Signaling through purinergic receptors for ATP induces human cutaneous innate and adaptive Th17 responses: implications in the pathogenesis of psoriasis. Killeen ME, Ferris L, Kupetsky EA, Falo L Jr, Mathers AR. Journal of immunology (Baltimore, Md. : 1950). 2013 190:4324-36. (IF; Human) [Full Text Article] [PubMed:23479230] [PMC:PMC3622186] Related Antibodies: LS-A9585.
2
Anti-apoptotic Effects of Bone Marrow on Human Islets: A Preliminary Report. Luo LG, Luo JZ. Journal of stem cell research & therapy. 2015 5: (IHC; Human) [Full Text Article] [PubMed:26229735] [PMC:PMC4517837] Related Antibodies: LS-A9585.

☰ Filters
Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
P2RX7 / P2X7 (4)
No (4)
GST (1)
His-TRX (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
P2RX7 / P2X7 Protein - Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 7 By SDS-PAGE
Select
E. coli
His-TRX
36.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
P2RX7 / P2X7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
68.4 kDa
20 µg/$215
P2RX7 / P2X7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
68.4 kDa
100 µg/$710
P2RX7 / P2X7 Protein - 12.5% SDS-PAGE of human P2RX7 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
94.9 kDa
2 µg/$439
Viewing 1-4 of 4 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).