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OTX1 is a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants.
Gene Name: | orthodenticle homeobox 1 |
Synonyms: | OTX1, Homeobox protein OTX1, Orthodenticle homeobox 1, Orthodenticle homolog 1 |
Target Sequences: | NM_014562 AAH07621.1 P32242 |
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