ORC2L / ORC2

origin recognition complex, subunit 2

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ORC2L / ORC2 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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ORC2L / ORC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115474

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.8 kDa

Price:

100 µg/$494

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Human ORC2L / ORC2 Protein (Recombinant GST) (Full Length) - LS-G29583

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

89.21 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ORC2L / ORC2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66492

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.8 kDa

Price:

20 µg/$1,107

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Human ORC2L / ORC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77830

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.8 kDa

Price:

20 µg/$150

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