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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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OPRS1 / SIGMAR1

sigma non-opioid intracellular receptor 1

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.

Gene Name: sigma non-opioid intracellular receptor 1
Synonyms: SIGMAR1, HSigmaR1, ALS16, SIG-1R, Sigma 1-type opioid receptor, SR-BP, Opioid receptor, sigma 1, OPRS1, Sigma1-receptor, SR31747-binding protein, SRBP, Sigma1R, SR-BP1, SR31747 binding protein 1
Target Sequences: NM_005866 NP_005857.1 Q99720

Filtered By: None
Target
OPRS1 / SIGMAR1 (13)
Reactivity
Human (13)
Mouse (4)
Rat (5)
Application
IHC (7)
IHC-P (2)
WB (9)
Flo (1)
ELISA (4)
Host
rabbit (13)
Isotype
IgG (9)
Clonality
polyclonal pc (13)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (10)
Epitope
Internal (1)
aa118-147 (1)
aa47-81 (1)
Publications
No (13)
Showing 1-13 of 13 results

OPRS1 / SIGMAR1 Antibody IHC-plus™ LS-B15555
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.

OPRS1 / SIGMAR1 Antibody LS-C401334
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human gastric cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human liver cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human gastric cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human liver cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.

OPRS1 / SIGMAR1 Antibody LS-C404611
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human gastric cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human liver cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human gastric cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human liver cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.

OPRS1 / SIGMAR1 Antibody LS-C751649
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Human
ELISA IHC WB
Unconjugated
100µg  $355.00

OPRS1 / SIGMAR1 Antibody LS-C672039
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Human
ELISA IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human colon cancer at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human colon cancer at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100

OPRS1 / SIGMAR1 Antibody (HRP) LS-C672040
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

OPRS1 / SIGMAR1 Antibody (Biotin) LS-C672042
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Human
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

OPRS1 / SIGMAR1 Antibody (FITC) LS-C672041
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Human
FITC Conjugated
50µg  $285.00; 100µg  $385.00

OPRS1 / SIGMAR1 Antibody LS-C341630
Rabbit Polyclonal to Human OPRS1 / SIGMAR1
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

OPRS1 / SIGMAR1 Antibody (Internal) LS-C145069
Rabbit Polyclonal to Human OPRS1 / SIGMAR1
Human
IHC WB
Unconjugated
100µl  $365.00

OPRS1 / SIGMAR1 Antibody (aa47-81) LS-C98622
Rabbit Polyclonal to Human OPRS1 / SIGMAR1
Human
Flo WB
Unconjugated
400µl  $305.00
Western blot of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
Flow cytometric of NCI-H292 cells using OPRS1 Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Western blot of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
Flow cytometric of NCI-H292 cells using OPRS1 Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

OPRS1 / SIGMAR1 Antibody LS-C749820
Rabbit Polyclonal (IgG) to Human OPRS1 / SIGMAR1
Rat, Human
WB
Unconjugated
50µl  $235.00

OPRS1 / SIGMAR1 Antibody (aa118-147) LS-C98623
Rabbit Polyclonal to Human OPRS1 / SIGMAR1
Human
WB
Unconjugated
400µl  $305.00
Western blot of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
OPRS1 Antibody western blot of mouse brain tissue lysates (35 ug/lane). The OPRS1 antibody detected the OPRS1 protein (arrow).
Western blot of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
OPRS1 Antibody western blot of mouse brain tissue lysates (35 ug/lane). The OPRS1 antibody detected the OPRS1 protein (arrow).
Showing 1-13 of 13 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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