OPN4 / Melanopsin

opsin 4

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Antibodies (9)

Type

Primary (9)

Target

OPN4 / Melanopsin (9)

Reactivity

Human (8)

Mouse (2)

Rat (1)

Application

IHC (1)

WB (9)

ELISA (2)

IF (3)

Peptide-ELISA (4)

Host

rabbit (8)

rabbit-new zealand white (1)

Isotype

IgG (6)

Clonality

polyclonal pc (9)

Format

Unconjugated (9)

Epitope

400-480 aa, C-terminal (1)

C-Terminus (1)

Leu470 (1)

aa421-470 (1)

aa429-478 (1)

Publications

No (8)

Yes (1)

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OPN4 / Melanopsin Antibody (400-480 aa, C-terminal) LS-C384509

(4.0) Rating

(1) Publication(s)

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal (400-480 aa, C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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OPN4 / Melanopsin Antibody (Leu470) LS-C177236

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal (Leu470) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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OPN4 / Melanopsin Antibody LS-C803818

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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OPN4 / Melanopsin Antibody (aa429-478) LS-C120810

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal (aa429-478) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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OPN4 / Melanopsin Antibody (C-Terminus) LS-C353612

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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OPN4 / Melanopsin Antibody LS-C805785

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

OPN4 / Melanopsin Antibody LS-C829614

Antibody:

OPN4 / Melanopsin Rabbit-New Zealand White anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

OPN4 / Melanopsin Antibody LS-C827045

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

OPN4 / Melanopsin Antibody (aa421-470) LS-C200297

Antibody:

OPN4 / Melanopsin Rabbit anti-Human Polyclonal (aa421-470) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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