OPA1

optic atrophy 1 (autosomal dominant)

Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.Dynamin-like 120 kDa protein, form S1: Inactive form produced by cleavage at S1 position by OMA1 following stress conditions that induce loss of mitochondrial membrane potential, leading to negative regulation of mitochondrial fusion.

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Products

ELISA Kits (2)

Type

Sandwich (2)

Target

OPA1 (2)

Reactivity

Human (1)

Rat (1)

Format

96-Well Microplate (2)

Publications

No (2)

Sample Type

Cell Lysates (2)

Tissue Homogenates (2)

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Human OPA1 (Sandwich ELISA) ELISA Kit - LS-F74387

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$595

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Rat OPA1 (Sandwich ELISA) ELISA Kit - LS-F74404

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$646

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