ONECUT1 / HNF6 is a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.
|Gene Name:||one cut homeobox 1|
|Synonyms:||ONECUT1, Hepatocyte nuclear factor 6, HNF6, One cut domain family member 1, One cut homeobox 1, HNF-6, HNF6A|
|Target Sequences:||U77975 AAB61705.1 Q9UBC0|
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