OFD1

oral-facial-digital syndrome 1

Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

OFD1 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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OFD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117207

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

116.5 kDa

Price:

100 µg/$710

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Human OFD1 Protein (Recombinant GST) (Full Length) - LS-G31170

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

89.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human OFD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85627

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

116.5 kDa

Price:

20 µg/$215

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