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OCA2 / P protein

oculocutaneous albinism II

Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color.

Gene Name: oculocutaneous albinism II
Family/Subfamily: Transporter , Arsenite resistance efflux pump
Synonyms: OCA2, BOCA, BEY1, BEY2, Brown Oculocutaneous Albinism, D15S12, Eye color 2 (central brown), EYCL2, Hair color 3 (brown), HCL3, Eye color 3 (brown), Total brown iris pigmentation, Oculocutaneous albinism II, Pink-eye dilution, SHEP1, BEY, EYCL, EYCL3, P protein, PED
Target Sequences: NM_000275 NP_000266.2 Q04671

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Antibodies (24)
Primary (24)
OCA2 / P protein (24)
Human (24)
Mouse (7)
Rat (6)
Bat (6)
Bovine (6)
Chimpanzee (6)
Dog (6)
Gibbon (3)
Guinea pig (6)
Hamster (3)
Horse (6)
Monkey (6)
Orangutan (3)
Pig (6)
Rabbit (6)
Zebrafish (3)
IHC (5)
IHC-P (4)
WB (20)
ELISA (9)
IF (1)
Peptide-ELISA (1)
rabbit (23)
mouse (1)
Product Group
IHCPlus (1)
IgG (16)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (23)
1A11 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (10)
aa111-138 (7)
aa430-479 (4)
aa468-517 (4)
No (24)
OCA2 / P protein Antibody - Anti-OCA2 / P Protein antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa468-517) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OCA2 / P protein Antibody - Anti-OCA2 / P Protein antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa468-517) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
OCA2 / P protein Antibody - Anti-OCA2 / P Protein antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa468-517) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
OCA2 / P protein Antibody - Anti-OCA2 / P Protein antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa468-517) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
OCA2 / P protein Antibody - Positive Western Blot detected in K562 whole cell lysate, 293T whole cell lysate, A549 whole cell lysate, U87 whole cell lysate, HL-60 whole cell lysate, Rat brain tissue. All lanes: OCA2 antibody at 8.93 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 93, 91, 75 KDa. Observed band size: 93 KDa
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OCA2 / P protein Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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OCA2 / P protein Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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OCA2 / P protein Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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OCA2 / P protein Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
OCA2 / P protein Antibody - Western blot analysis of 293T whole cells lysates using OCA2 antibody. The lane on the left is treated with the antigen-specific peptide.
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OCA2 / P protein Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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OCA2 / P protein Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
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OCA2 / P protein Mouse anti-Human Monoclonal (1A11) Antibody
Human
ELISA
Unconjugated
100 µg/$423
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OCA2 / P protein Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
OCA2 / P protein Antibody - Western blot of Human OVCAR-3. OCA2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa430-479) Antibody
Human
WB
Unconjugated
100 µl/$424
OCA2 / P protein Antibody - Western blot of Human OVCAR-3. OCA2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa430-479) (HRP) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Orangutan, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
OCA2 / P protein Antibody - Western blot of Human OVCAR-3. OCA2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa430-479) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Orangutan, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
OCA2 / P protein Antibody - Western blot of Human OVCAR-3. OCA2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa430-479) (FITC) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Orangutan, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
OCA2 / P protein Antibody - OCA2 Antibody western blot of 293 cell line lysates (35 ug/lane). The OCA2 antibody detected the OCA2 protein (arrow).
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OCA2 / P protein Rabbit anti-Human Polyclonal (aa111-138) Antibody
Human
WB
Unconjugated
400 µl/$393
OCA2 / P protein Antibody - Western blot analysis of extracts of various cell lines.
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OCA2 / P protein Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).