OAZ1 / OAZ

ornithine decarboxylase antizyme 1

OAZ1 / OAZ belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

OAZ1 / OAZ (3)

Publications

No (3)

Tag

His (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Purification

Purified (1)

Select

OAZ1 / OAZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116837

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.22 kDa

Price:

100 µg/$494

Select

Human OAZ1 / OAZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77832

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.22 kDa

Price:

20 µg/$150

Select

Human OAZ1 / OAZ Protein (Recombinant His) - LS-G1910

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.