Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 610/620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.

Gene Name: 2'-5'-oligoadenylate synthetase 2, 69/71kDa
Synonyms: OAS2, 2-5A synthase 2, 2-5-oligoadenylate synthase 2, p69OAS / p71OAS, p69 OAS / p71 OAS
Target Sequences: NM_002535 NP_002526.2 P29728

☰ Filters
Products
Antibodies (50)
Primary (50)
OAS2 (50)
Human (50)
Mouse (1)
Rat (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Horse (3)
Monkey (3)
Orangutan (6)
Pig (6)
Rabbit (3)
IHC (12)
IHC-P (2)
WB (42)
ELISA (10)
ICC (1)
IF (2)
IP (1)
Peptide-ELISA (3)
rabbit (28)
mouse (20)
goat (2)
Product Group
IHCPlus (1)
IgG (16)
IgG1 (10)
IgG2a (8)
IgG2b (2)
monoclonal mc (20)
polyclonal pc (30)
OTI2A1 (2)
OTI2G3 (2)
OTI3A3 (2)
OTI3C1 (2)
OTI3D4 (2)
OTI4B11 (2)
OTI5C10 (2)
OTI5C3 (2)
OTI5E1 (2)
OTI6E6 (2)
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (10)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (31)
aa60-335 (20)
aa11-346 (8)
C-Terminus (7)
aa35-84 (4)
aa398-447 (4)
Internal Region (1)
Internal region (near N-Terminus) (1)
No (50)
OAS2 Antibody - Anti-OAS2 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
OAS2 Goat anti-Human Polyclonal (Internal Region) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
OAS2 Antibody - Western blot analysis of extracts of Jurkat cells using OAS2 antibody. The lane on the left was treated with blocking peptide.
Select
OAS2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
OAS2 Antibody - Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
OAS2 Rabbit anti-Human Polyclonal (aa398-447) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
OAS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
OAS2 Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-OAS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI5E1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
OAS2 Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-OAS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (Carrier-free) (OTI5E1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
OAS2 Antibody - Immunofluorescence staining of OAS2 in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human OAS2 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Nucleus and Cytoplasm.
Select
OAS2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$737
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$1,002
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$1,002
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$1,002
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (AP) Antibody
Human
ELISA, IHC
AP Conjugated
200 µl/$1,002
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$1,002
Select
OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$1,002
Select
OAS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
OAS2 Antibody - Western Blot analysis of extracts from HeLa cells using OAS2 Antibody.
Select
OAS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
OAS2 Antibody - OAS2 antibody (1 ug/ml) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
OAS2 Goat anti-Human Polyclonal (Internal region (near N-Terminus)) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$493
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI2G3) Antibody
Human
WB
Unconjugated
100 µl/$434
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI4B11) Antibody
Human
WB
Unconjugated
100 µl/$434
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI2A1) Antibody
Human
WB
Unconjugated
100 µl/$434
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI3C1) Antibody
Human
WB
Unconjugated
100 µl/$434
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI6E6) Antibody
Human
WB
Unconjugated
100 µl/$434
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (Carrier-free) (OTI6E6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI3A3) Antibody
Human
WB
Unconjugated
100 µl/$434
OAS2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
Select
OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI5C10) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 50 product results


Filtered By:
Products: Antibodies


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).