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Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
Gene Name: | nucleoredoxin |
Synonyms: | NXN, Nucleoredoxin 1, Nucleoredoxin, NRX, TRG-4 |
Target Sequences: | NM_022463 NP_071908.2 Q6DKJ4 |
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