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NUP62

nucleoporin 62kDa

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.

Gene Name: nucleoporin 62kDa
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: NUP62, 62 kDa nucleoporin, IBSN, Nucleoporin 62kD, Nucleoporin 62kDa, p62, SNDI, Nuclear pore glycoprotein p62
Target Sequences: NM_016553 NP_036478.2 P37198

Publications (1)

1
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology10<sup> Department of Pathology, University of Pittsburgh, Pittsburgh, United States. Eric N Anderson, Andrés A Morera, Sukhleen Kour, Jonathan D Cherry , Nandini Ramesh, Amanda Gleixner , Jacob C Schwartz, Christopher Ebmeier, William Old, Christopher J Donnelly , Jeffrey P Cheng, Anthony E Kline , Julia Kofler, Thor D Stein , Udai Bhan Pandey. eLife. 2021 May;10:e67587. [Full Text Article] [PubMed:34060470] [PMC:PMC8169113]

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Products
Proteins (11)
Over-Expression Lysate (6)
Recombinant (5)
NUP62 (11)
No (11)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (7)
Human (8)
293T Cells (3)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
NUP62 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
53.7 kDa
100 µg/$494
NUP62 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
53.7 kDa
100 µg/$494
NUP62 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
53.7 kDa
100 µg/$494
NUP62 Protein
Select
E. coli
His, N-Terminal
53.3 kDa
50 µg/$419
NUP62 Protein - Recombinant  Nucleoporin 62kDa By SDS-PAGE
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E. coli
His-T7
29.0 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
NUP62 Protein - 12.5% SDS-PAGE of human NUP62 stained with Coomassie Blue
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Wheat Germ Extract
GST
82.94 kDa
10 µg/$479; 25 µg/$670
NUP62 Protein - Purified recombinant protein NUP62 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.1 kDa
20 µg/$1,107
NUP62 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NUP62 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
53.7 kDa
20 µg/$150
NUP62 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
53.7 kDa
20 µg/$150
NUP62 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
53.7 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).