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The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene.
Gene Name: | nucleoporin 54kDa |
Synonyms: | NUP54, 54 kDa nucleoporin, Nucleoporin 54kD, Nucleoporin 54kDa, Nucleoporin p54 |
Target Sequences: | NM_017426 NP_059122.2 Q7Z3B4 |
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