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NUDT9

nudix (nucleoside diphosphate linked moiety X)-type motif 9

NUDT9 belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: nudix (nucleoside diphosphate linked moiety X)-type motif 9
Family/Subfamily: Transporter , Nudix
Synonyms: NUDT9, ADP-ribose phosphohydrolase, ADPR-PPase, ADP-ribose diphosphatase, Nudix motif 9
Target Sequences: NM_024047 NP_076952.1 Q9BW91

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).