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NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
NUDT9 belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | nudix (nucleoside diphosphate linked moiety X)-type motif 9 |
| Family/Subfamily: | Transporter , Nudix |
| Synonyms: | NUDT9, ADP-ribose phosphohydrolase, ADPR-PPase, ADP-ribose diphosphatase, Nudix motif 9 |
| Target Sequences: | NM_024047 NP_076952.1 Q9BW91 |
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