NUDEL / NDEL1

nudE neurodevelopment protein 1-like 1

Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

NUDEL / NDEL1 (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (7)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human NUDEL / NDEL1 Protein (Recombinant GST) (Full Length) - LS-G35504

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64.8 kDa

Price:

10 µg/$479; 25 µg/$670

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NUDEL / NDEL1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109395

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.2 kDa

Price:

100 µg/$494

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NUDEL / NDEL1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120992

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.9 kDa

Price:

100 µg/$494

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Human NUDEL / NDEL1 Protein (Recombinant His) - LS-G3005

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human NUDEL / NDEL1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72752

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.9 kDa

Price:

20 µg/$1,107

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Human NUDEL / NDEL1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72754

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.2 kDa

Price:

20 µg/$1,107

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Human NUDEL / NDEL1 Protein (Recombinant GST, N-terminus) (aa1-345) - LS-G57561

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human NUDEL / NDEL1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93495

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.9 kDa

Price:

20 µg/$150

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Human NUDEL / NDEL1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93496

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.2 kDa

Price:

20 µg/$150

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