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NUCKS1 encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
Gene Name: | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
Synonyms: | NUCKS1, JC7, Potential LAG1 interactor, NUCKS, p1 |
Target Sequences: | NM_022731 NP_073568.2 Q9H1E3 |
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