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NUBPL is a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. Mutations in this gene cause mitochondrial complex I deficiency. Alternative splicing results in multiple transcript variants.
Gene Name: | Nucleotide Binding Protein-like |
Synonyms: | NUBPL, IND1 homolog, Iron-sulfur protein NUBPL, HuInd1, C14orf127, IND1 |
Target Sequences: | NM_025152 NP_079428.2 Q8TB37 |
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