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NTSR2 / NTR2

neurotensin receptor 2

NTSR2 / NTR2 belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.

Gene Name: neurotensin receptor 2
Family/Subfamily: GPCR , Neurotensin
Synonyms: NTSR2, Neurotensin NT2 receptor, Neurotensin receptor, type 2, NTR2, NT2 receptor, Neurotensin receptor 2, Neurotensin receptor type 2, NT-R-2
Target Sequences: NM_012344 NP_036476.1 O95665

Publications (1)

1
Identification of molecular tumor markers in renal cell carcinomas with TFE3 protein expression by RNA sequencing. Pflueger D, Sboner A, Storz M, Roth J, Compérat E, Bruder E, Rubin MA, Schraml P, Moch H. Neoplasia (New York, N.Y.). 2013 15:1231-40. (IHC; Human) [PubMed:24339735] [PMC:PMC3859447] Related Antibodies: LS-A1265.

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NTSR2 / NTR2 (2)
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Tissue Homogenates (1)
NTSR2 / NTR2 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
NTSR2 / NTR2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).